Abstract Search

ea0098o2 | Other | NANETS2023

Germline testing identifies pathogenic/likely pathogenic variants in patients with pancreatic neuroendocrine tumors

Mohindroo Chirayu , Baydogan Seyda , Agarwal Parul , Laheru Dan , Wright Robin , Prakash Laura R. , Mork Maureen E. , Klein Alison P. , Maxwell Jess , H.G. Katz Matthew , Dasari Arvind , Kim Michael P. , He Jin , McAllister Florencia , De Jesus-Acosta Ana

Background: 10% of pancreatic neuroendocrine tumors (pNETs) are thought to be related to inherited syndromes, (MEN1, MEN4, VHL, NF1 and TSC). Growing evidence suggests, that clinically sporadic appearing pNETs can harbor germline mutations. Here, we report the prevalence of pathological/likely pathological germline variants (P/LP) in 2 cohorts: 1) High-risk and 2) Unselected.Methods: We retrospectively collected clinical data of pNET patients seen at MD ...

0 shares

Endocrine Abstracts

Germline testing identifies pathogenic/likely pathogenic variants in patients with pancreatic neuroendocrine tumors

BiosciAbstracts